Centre County 911 says a part of Rt. 322 (Mount Nittany Expy) east of State College has reopened after being shut down for an extended period of time.
All lanes were closed at the 45 East - Old Fort exit and traffic was redirected to Boal Ave.
According to 511PA, the closure was because of a multi-vehicle crash.
A Facebook post by Centre County 911 said: "Please avoid the area and adjust your travels accordingly. The orange detour will be put in place for EB traffic (State College to Lewistown)"
Nabil Mark, the media and communications manager for the State College Area School District, said there could be bus delays because of traffic congestion.
"This could affect buses with State High, Mount Nittany Middle and Mount Nittany Elementary students," Mark said.
Mark said anyone with questions can contact the transportation office at 814-231-1033 or your school.